Can Solgar Evening Primrose Oil Help with Liver Disease?
Research Authors
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Moderately Good
Based on 23 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil (Seed) providing:
1300 mg
***
Linoleic Acid
949 mg
***
Gamma-Linolenic Acid
117 mg
***
Top Medical Research Studies
8
Evening primrose oil mitigates liver damage
Evening primrose oil enriched with gamma linolenic acid and D/L-alpha tocopherol acetate attenuated carbon tetrachloride-induced hepatic injury model in male rats via TNF-α, IL-1β, and IL-6 pathway.
We investigated how evening primrose oil, enhanced with gamma-linolenic acid and D/L-alpha tocopherol, could protect against liver damage in a rat model. In this study, male rats were divided into four groups, including a control and treatment group.
We found that the evening primrose oil group showed improvements in liver health compared to those exposed to carbon tetrachloride, a harmful substance. While liver enzymes returned to safer levels and tissue damage was reduced, the oil’s effectiveness emphasizes its potential benefits for supporting liver health.
Read More
4
No significant effect on survival
The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial.
We investigated the effects of evening primrose oil, which contains gamma-linolenic acid (GLA), on primary liver cancer in a double-blind placebo-controlled trial. Unfortunately, we found that while there was no significant impact on survival time or liver size, the treatment did show a beneficial effect on liver function as indicated by improvements in Gamma Glutamyl transferase values. Importantly, participants experienced no side effects, suggesting it could be a safe option, though the large tumors and low doses used might explain the limited effects on survival.
Read More
Most Useful Reviews
9
Improved menstrual cycle
60 people found this helpful
Indispensable for women's health, I use it in the complex treatment of endometriosis at a dosage of 1300 mg twice a day. Primrose contains gamma linolenic acid (GLA), which suppresses inflammatory and autoimmune processes. What have I noticed? Critical days have become quite regular, without pain or spasms. Hormones are balanced, with no bias towards oestrogen. It is suitable for women with painful menstrual cycles and to prevent oestrogen-dependent diseases. It reduces unpleasant symptoms, such as hot flashes, during the climacteric period.
Read More
7.5
Balanced hormones
15 people found this helpful
Magic primrose for female beauty! I purchased this to improve hormonal levels, which helped to alleviate premenstrual symptoms. It moisturises the skin effectively. It contains essential linoleic and linolenic acids found in evening primrose seeds. This oil has anti-inflammatory properties, helps strengthen immunity, and normalises hormonal balance. It has a positive impact on the genitourinary system, eases menopause symptoms, and reduces menstrual irregularities.
Read More
9
Enhanced reproductive health
14 people found this helpful
Evening primrose oil offers numerous benefits for women, especially in normalising hormonal balance and alleviating PMS symptoms. While I sought help for fibrocystic issues and reproductive pain, this supplement has also proven useful for male hormonal disorders. It supports liver cleansing and enhances overall health. Regular use can help mitigate the risk of strokes and heart attacks and improve skin health significantly.
Evening primrose oil enriched with gamma linolenic acid and D/L-alpha tocopherol acetate attenuated carbon tetrachloride-induced hepatic injury model in male rats via TNF-α, IL-1β, and IL-6 pathway.
We investigated how evening primrose oil, enhanced with gamma-linolenic acid and D/L-alpha tocopherol, could protect against liver damage in a rat model. In this study, male rats were divided into four groups, including a control and treatment group.
We found that the evening primrose oil group showed improvements in liver health compared to those exposed to carbon tetrachloride, a harmful substance. While liver enzymes returned to safer levels and tissue damage was reduced, the oil’s effectiveness emphasizes its potential benefits for supporting liver health.
Read More
4
No significant effect on survival
The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial.
We investigated the effects of evening primrose oil, which contains gamma-linolenic acid (GLA), on primary liver cancer in a double-blind placebo-controlled trial. Unfortunately, we found that while there was no significant impact on survival time or liver size, the treatment did show a beneficial effect on liver function as indicated by improvements in Gamma Glutamyl transferase values. Importantly, participants experienced no side effects, suggesting it could be a safe option, though the large tumors and low doses used might explain the limited effects on survival.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 23 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Improved menstrual cycle
60 people found this helpful
Indispensable for women's health, I use it in the complex treatment of endometriosis at a dosage of 1300 mg twice a day. Primrose contains gamma linolenic acid (GLA), which suppresses inflammatory and autoimmune processes. What have I noticed? Critical days have become quite regular, without pain or spasms. Hormones are balanced, with no bias towards oestrogen. It is suitable for women with painful menstrual cycles and to prevent oestrogen-dependent diseases. It reduces unpleasant symptoms, such as hot flashes, during the climacteric period.
Read More
7.5
Balanced hormones
15 people found this helpful
Magic primrose for female beauty! I purchased this to improve hormonal levels, which helped to alleviate premenstrual symptoms. It moisturises the skin effectively. It contains essential linoleic and linolenic acids found in evening primrose seeds. This oil has anti-inflammatory properties, helps strengthen immunity, and normalises hormonal balance. It has a positive impact on the genitourinary system, eases menopause symptoms, and reduces menstrual irregularities.
Read More
9
Enhanced reproductive health
14 people found this helpful
Evening primrose oil offers numerous benefits for women, especially in normalising hormonal balance and alleviating PMS symptoms. While I sought help for fibrocystic issues and reproductive pain, this supplement has also proven useful for male hormonal disorders. It supports liver cleansing and enhances overall health. Regular use can help mitigate the risk of strokes and heart attacks and improve skin health significantly.
Read More
9
Softer PMS experience
5 people found this helpful
Wonderful! I ordered it for myself and my mother, aiming to prevent female diseases post-menopause. After one bottle, I noticed my PMS was more manageable and the breast tenderness was gone. The menstruation itself was less painful, and I wholeheartedly recommend it.
Read More
9
Cycle restoration miracle
3 people found this helpful
After struggling with polycystic ovarian syndrome and liver issues, I discovered evening primrose oil. This natural remedy restored my menstrual cycle remarkably. I used to rely heavily on hormonal pills, but this oil has alleviated those issues and even assisted in my pregnancy. My body feels more in tune now, particularly after shifting to a sustainable intake approach.
Liver disease encompasses a variety of conditions that affect the liver's ability to function effectively. The liver is a vital organ responsible for many important tasks, including metabolizing nutrients, detoxifying harmful substances, and producing bile for digestion. Common forms of liver disease include hepatitis, fatty liver disease, cirrhosis, and liver cancer. Each of these conditions can significantly impact liver function and overall health, leading to symptoms that range from fatigue and jaundice to more serious complications requiring urgent medical attention.
The causes of liver disease are diverse and can include chronic alcohol abuse, viral infections, autoimmune disorders, and metabolic conditions like obesity and diabetes. Early detection is key to managing liver disease effectively, often involving lifestyle changes, medications, and sometimes surgical interventions. Regular check-ups and liver function tests are recommended for individuals at higher risk, such as those with a family history of liver disease or those who lead certain lifestyle habits. Adopting a balanced diet and reducing alcohol intake can greatly aid in liver health and help prevent the onset of these conditions.
Evening Primrose Oil is derived from the seeds of the evening primrose plant (Oenothera biennis), a native North American flowering plant known for its bright yellow blooms that open in the evening. This oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid that plays a crucial role in various bodily functions, including maintaining skin health and regulating inflammation. Due to its high GLA content, evening primrose oil is often used as a dietary supplement to assist with a variety of health concerns, such as symptoms associated with premenstrual syndrome (PMS), menopause, and conditions that involve inflammation like eczema.
In addition to its potential health benefits when taken in supplement form, many users also apply evening primrose oil topically to help improve skin health, reduce dryness, and soothe irritations. While some research supports its benefits, results can vary, and it’s always recommended to consult with a healthcare professional before adding any new supplement to your routine. Overall, evening primrose oil is celebrated for its versatility as both a dietary and topical addition, making it a popular choice among those seeking natural wellness options.
Based on user reviews, the time it typically takes to see results from taking evening primrose oil for liver disease and hormonal issues can vary significantly. Many users report noticeable improvements after a few weeks of consistent use. For instance, one user noted that after consuming about one-third of the bottle, they experienced a significant decrease in pain associated with their condition, though they did not specify an exact timeframe (Read Review). Another user indicated they observed improvements in their symptoms after just two weeks of intake, which highlights the potential for relatively quick effects (Read Review).
However, it is crucial to consider that individual experiences may vary widely. Some may notice changes sooner, while others might take longer to experience the supplement's full effects. For optimal results, many suggest maintaining a consistent dosing routine over a period of one to two months to fully assess the benefits. In summary, while some users describe quick relief, others have experienced gradual improvement, underscoring the importance of patience in the pursuit of health with evening primrose oil (Read Review).
Evening primrose oil has shown promise in promoting liver health according to a couple of scientific studies. One study involving rats demonstrated that evening primrose oil could help protect against liver damage by improving liver health parameters, such as reducing enzyme levels and tissue damage caused by harmful substances like carbon tetrachloride [1]. These findings suggest that evening primrose oil might be beneficial for individuals looking to support liver health.
Another study explored the impact of evening primrose oil on liver cancer in a clinical trial setting. While the oil did not significantly enhance survival or reduce tumor size, there were notable improvements in liver function metrics, particularly regarding Gamma Glutamyl transferase levels [2]. This indicates that evening primrose oil may be a safe adjunct treatment option for liver function enhancement, although its effects on severe liver conditions like cancer may be limited. Overall, while more extensive research is warranted, evening primrose oil shows potential in liver health maintenance.
Based on user reviews, many individuals have reported significant improvements in their symptoms related to hormonal balance and menstrual discomfort after using evening primrose oil. Numerous users noted that their menstrual cycles became more regular and less painful. For instance, one user highlighted that after starting a daily dosage, both premenstrual symptoms and menstrual pains significantly decreased, leading to a more manageable experience during their critical days (Read Review). Similarly, another reviewer stated that their PMS was vastly improved and that they experienced less pain and discomfort with their menstrual cycles after using this oil regularly (Read Review).
In addition to menstrual symptom relief, users have praised the oil's ability to alleviate menopausal symptoms such as hot flashes and hormonal imbalances. A user noted a remarkable reduction in hot flashes within just three days of starting to take the oil, suggesting a quick response in certain individuals (Read Review). Others have reported improvements in skin health and overall well-being, likely attributable to the oil’s anti-inflammatory properties and its support in maintaining hormonal balance (Read Review). Keep in mind that while many users experience these benefits, individual results can vary widely, highlighting the importance of consistency and consultation with a healthcare provider for optimal dosing and effects.
Based on user reviews, many individuals have reported positive experiences when combining evening primrose oil with other supplements for managing liver disease and hormonal issues. One user highlighted that they took evening primrose oil alongside DIM, green tea, vitex, omega-3, and a liver support supplement, which resulted in a notably smoother menstrual cycle and a decrease in PMS symptoms (Read Review). Others also suggested that evening primrose oil, when used in conjunction with other remedies, can offer synergistic benefits for improved hormonal balance and overall health, particularly for addressing conditions like mastopathy (Read Review).
Moreover, some users emphasized the importance of seeking professional guidance when considering a combination of supplements. For instance, one reviewer advised consulting with a doctor for dosage recommendations to optimize results and effectively handle menstrual irregularities as well as support liver health (Read Review). Overall, while combining evening primrose oil with other supplements appears to be well-received among users, individual outcomes may vary, making personalized consultation with a healthcare provider essential for tailored strategies.
Based on user reviews, the optimal dosage for Evening Primrose Oil in relation to liver disease appears to vary, but many suggest around 1300 mg is beneficial. For instance, one user who successfully managed endometriosis reported taking 1300 mg twice a day, highlighting the oil's anti-inflammatory properties and its positive impact on hormonal balance Read Review. Other users indicated that they experienced significant improvements in their menstrual cycles and overall well-being when taking Evening Primrose Oil consistently, supporting liver health alongside other benefits Read Review.
Importantly, individual experiences suggest that combining Evening Primrose Oil with other supplements enhances its effectiveness for managing conditions such as PMS or hormonal imbalances, which may intersect with liver health. One user noted a moderate dose of two capsules daily over two weeks led to successfully balancing hormones, albeit with caution advised for those with autoimmune issues Read Review. Overall, users recommend consulting healthcare professionals for personalized dosage guidance to optimize benefits, particularly when addressing more complex health concerns like liver disease and hormonal imbalances Read Review.
8
Significant pain relief
1 people found this helpful
I have suffered from women's pains for 10 years. Tired of painkillers, I became concerned for my liver as I aged. After researching various remedies, I began taking evening primrose oil. While effects weren't immediate, after consuming about one-third of the bottle, my pain notably decreased (previously it was excruciating for the first 2-3 days). Overall, I am very satisfied with this product’s impact.
4
Effective for pregnancy
3 people found this helpful
This oil truly works! It helped me conceive. I initially used evening primrose oil to balance hormones, knowing its success rate for many. I took it for two weeks with two capsules daily. After that, I developed red spots and stopped. However, two weeks later I fell pregnant. This oil, rich in OMEGA-6 PUFA, should be avoided with autoimmune conditions as it can trigger inflammation. For hormonal imbalance, it proved highly effective in my case.
7.5
Improved menstrual cycle
411 people found this helpful
Evening Primrose Oil, which is rich in gamma-linolenic acid (Omega 6), is beneficial for women’s health. Regular intake can regulate menstruation, ease PMS symptoms, and enhance reproductive functions. I’ve noticed positive changes; my menstrual cycle is now regular, pain has significantly decreased, and my skin has improved remarkably. It's essential to take the oil consistently for the best results, and I found capsules effective. If you are not pregnant, I recommend taking one capsule twice daily for two months, then take a break.
9
Improved menstrual cycle
60 people found this helpful
Indispensable for women's health, I use it in the complex treatment of endometriosis at a dosage of 1300 mg twice a day. Primrose contains gamma linolenic acid (GLA), which suppresses inflammatory and autoimmune processes. What have I noticed? Critical days have become quite regular, without pain or spasms. Hormones are balanced, with no bias towards oestrogen. It is suitable for women with painful menstrual cycles and to prevent oestrogen-dependent diseases. It reduces unpleasant symptoms, such as hot flashes, during the climacteric period.
7.5
Skin and PMS relief
134 people found this helpful
Evening primrose oil is renowned for its restorative and antioxidant qualities. I have personally found it beneficial for skin disorders, digestive issues, and liver disease. It also enhances women's reproductive health. Since I began taking it, PMS has vastly improved, and I experience no pain. A friend found relief from severe pain caused by her condition after using this oil. I believe this oil, especially from Solgar, is a trusted choice during summer for optimal effects.
9
Effective menopause solution
1 people found this helpful
Useful, especially for older women! My mother, aged 56, uses this oil to reduce hot flashes and moments of discomfort during menopause. Unlike her previous experience with a different brand, this Solgar oil worked swiftly from the first capsule! Her hot flashes disappeared by day three. Now, she feels much better and has no recurring feelings of fear in the morning, possibly due to improved hormonal balance. I highly recommend it!
7.5
Balanced hormones
15 people found this helpful
Magic primrose for female beauty! I purchased this to improve hormonal levels, which helped to alleviate premenstrual symptoms. It moisturises the skin effectively. It contains essential linoleic and linolenic acids found in evening primrose seeds. This oil has anti-inflammatory properties, helps strengthen immunity, and normalises hormonal balance. It has a positive impact on the genitourinary system, eases menopause symptoms, and reduces menstrual irregularities.
7.5
Improved menstrual experience
1 people found this helpful
I’m using it for endometriosis and hormonal balance! It took me a while to decide, as opinions vary. I combine it with DIM, green tea, vitex, omega-3, and a liver support supplement. My first period while taking it was surprisingly smooth, with no PMS—quite shocking! Though I still experienced some abdominal pain, the improvement in chest fullness is noteworthy, indicating that the product is effective. I look forward to consulting a doctor for further insights.
9
Effective in conception support
3 people found this helpful
Evening primrose oil, dosed correctly, has shown advantages for managing menstrual pain and aiding in conception. I have discovered that combining it with other supplements offers the best results, particularly for addressing mastopathy. I recommend consulting a doctor for dosage guidance, especially if menstrual irregularities occur. My experience has shown that it can support hormonal balance effectively.
8
Evening primrose oil mitigates liver damage
Evening primrose oil enriched with gamma linolenic acid and D/L-alpha tocopherol acetate attenuated carbon tetrachloride-induced hepatic injury model in male rats via TNF-α, IL-1β, and IL-6 pathway.
We investigated how evening primrose oil, enhanced with gamma-linolenic acid and D/L-alpha tocopherol, could protect against liver damage in a rat model. In this study, male rats were divided into four groups, including a control and treatment group.
We found that the evening primrose oil group showed improvements in liver health compared to those exposed to carbon tetrachloride, a harmful substance. While liver enzymes returned to safer levels and tissue damage was reduced, the oil’s effectiveness emphasizes its potential benefits for supporting liver health.
4
No significant effect on survival
The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial.
We investigated the effects of evening primrose oil, which contains gamma-linolenic acid (GLA), on primary liver cancer in a double-blind placebo-controlled trial. Unfortunately, we found that while there was no significant impact on survival time or liver size, the treatment did show a beneficial effect on liver function as indicated by improvements in Gamma Glutamyl transferase values. Importantly, participants experienced no side effects, suggesting it could be a safe option, though the large tumors and low doses used might explain the limited effects on survival.
References
Gad El-Hak HN, Kishk SM, Abdelrazek HMA. Evening primrose oil enriched with gamma linolenic acid and D/L-alpha tocopherol acetate attenuated carbon tetrachloride-induced hepatic injury model in male rats via TNF-α, IL-1β, and IL-6 pathway. Toxicol Mech Methods. 2024;34:469. doi:10.1080/15376516.2023.2301357
van der Merwe CF, Booyens J, Joubert HF, van der Merwe CA. The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trial. Prostaglandins Leukot Essent Fatty Acids. 1990;40:199.